Chemical components of the volatile and non-volatile extractives of Croton species and their microbial activities

Essential oil compounds of Croton pseudopulchellus and gratissimus were analysed using Gas Chromatography/Mass Spectrophotometry screened for antimicrobial activity against Bacillus pimilus (ATCC 29212), cereus 10702), Staphylococcus aureus 3983), Streptococcus faecalis Escherichia coli 4983), Klebsiella pneumoniae 2983) Pseudomonas aeruginosa 19582) Agar gel disk diffusion test minimum inhibitory concentrations. The susceptibilities all isolates different essential standardised by National Committee Clinical Laboratory Standards (NCCLS) 1998). cytotoxicity was also carried out to determine the toxicity levels compounds. These plants selected based on their use traditional healers treatment upper respiratory tract, gastrointestinal tract urinary infections. C. found be active microorganisms, while preliminary assessment from these exhibited low cytotoxic activity.   Key words: oil, sesquiterpenes, chemical composition,